Scientists Uncover a Never-Before-Seen Type of Signal Occurring in The Human Brain - Physics-Astronomy.org

Scientists Uncover a Never-Before-Seen Type of Signal Occurring in The Human Brain

Scientists have discovered a unique form of cell messaging occurring in the human brain that's not been seen before.Excitingly, the discovery hints that our brains might be even more powerful units of computation than we realised.




Researchers from institutes in Germany and Greece uncovered a mechanism in the brain's outer cortical cells that produces a novel 'graded' signal all on its own, one that could provide individual neurons with another way to carry out their logical functions.
By measuring the electrical activity in sections of tissue removed during surgery on epileptic patients and analysing their structure using fluorescent microscopy, the neurologists found individual cells in the cortex used not just the usual sodium ions to 'fire', but calcium as well.
This combination of positively charged ions kicked off waves of voltage that had never been seen before, referred to as a calcium-mediated dendritic action potentials, or dCaAPs.
Brains – especially those of the human variety – are often compared to computers. The analogy has its limits, but on some levels they perform tasks in similar ways.


Both use the power of an electrical voltage to carry out various operations. In computers it's in the form of a rather simple flow of electrons through intersections called transistors.
In neurons, the signal is in the form of a wave of opening and closing channels that exchange charged particles such as sodium, chloride, and potassium. This pulse of flowing ions is called an action potential.
Instead of transistors, neurons manage these messages chemically at the end of branches called dendrites.
"The dendrites are central to understanding the brain because they are at the core of what determines the computational power of single neurons," Humboldt University neuroscientist Matthew Larkum told Walter Beckwith at the American Association for the Advancement of Science.
Dendrites are the traffic lights of our nervous system. If an action potential is significant enough, it can be passed on to other nerves, which can block or pass on the message.
This is the logical underpinnings of our brain – ripples of voltage that can be communicated collectively in two forms: either an AND message (if x and y are triggered, the message is passed on); or an OR message (if x or y is triggered, the message is passed on).
Arguably, nowhere is this more complex than in the dense, wrinkled outer section of the human central nervous system; the cerebral cortex. The deeper second and third layers are especially thick, packed with branches that carry out high order functions we associate with sensation, thought, and motor control.


It was tissues from these layers that the researchers took a close look at, hooking up cells to a device called a somatodendritic patch clamp to send active potentials up and down each neuron, recording their signals.
"There was a 'eureka' moment when we saw the dendritic action potentials for the first time," said Larkum.
To ensure any discoveries weren't unique to people with epilepsy, they double checked their results in a handful of samples taken from brain tumours.
While the team had carried out similar experiments on rats, the kinds of signals they observed buzzing through the human cells were very different.
More importantly, when they dosed the cells with a sodium channel blocker called tetrodotoxin, they still found a signal. Only by blocking calcium did all fall quiet.
Finding an action-potential mediated by calcium is interesting enough. But modelling the way this sensitive new kind of signal worked in the cortex revealed a surprise.
In addition to the logical AND and OR-type functions, these individual neurons could act as 'exclusive' OR (XOR) intersections, which only permit a signal when another signal is graded in a particular fashion.
"Traditionally, the XOR operation has been thought to require a network solution," the researchers write.
More work needs to be done to see how dCaAPs behave across entire neurons, and in a living system. Not to mention whether it's a human-thing, or if similar mechanisms have evolved elsewhere in the animal kingdom.


Technology is also looking to our own nervous system for inspiration on how to develop better hardware; knowing our own individual cells have a few more tricks up their sleeves could lead to new ways to network transistors.
Exactly how this new logic tool squeezed into a single nerve cell translates into higher functions is a question for future researchers to answer.
This research was published in Science.

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  15. I never believed that i will be happy again after much frustration. I have been rejected by my husband after Six(6) years of marriage just because he met another woman and he left me and the kids to suffer. One day when i was reading through the web i stumbled at a post on how chief dr lucky the great spell caster has helped people to restore broken marriages and relationships and curing of diseases. I emailed him immediately to help my situation via: chiefdrlucky@gmail.com He told me not to worry that my husband will return to me begging and shedding tears of forgiveness. I am so happy that my husband actually returned to me in 48 hours after i obeyed the words and instructions of chief dr lucky. contact him today in any of your problems for a lasting solution via: chiefdrlucky@gmail.com or call/whats app +2348132777335 Website: http://chiefdrluckysolutionhome.website2.me/  

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  16. Please visit (http://solutiontemples.com) to get your ex back immediately
    WHO SO EVER IS READING THIS TESTIMONY TODAY SHOULD PLEASE CELEBRATE WITH ME BECAUSE AM SO HAPPY FOR THE GREAT WORK DR.Ikhile DID FOR ME.
    I am Miss Sonia from New york, I promise Dr Ikhile to share this testimony all over the world once my boyfriend return back to me, and today with all due respect i want to thank DR.Ikhile for bringing joy and happiness to my relationship and my family. I want to inform you all that there is a spell caster that is real and genuine. I never believed in any of these things until i loosed my boyfriend, I required help until i found Website:http://solutiontemples.com A great spell caster, And he cast a love spell for me, and he assured me that I will get my boyfriend back in just 24hours after the spell has been cast. 24hours later, my phone rang, and so suppricinly , it was my boyfriend who has not called me for past 1year now, and he made an apology for the heart break, and told me that he is ready to be my back bone till the rest of his life with me. DR.Ikhile Email solutiontemple27@gmail.com released him, to know how much i loved and wanted him. And opened his eyes to picture how much love we have share together. As I am writing this testimony right now i am the most happiest woman on earth and me and my fiance is living a happy life and our love is now stronger than how it were even before our break up. So that is why I promised to share my testimony all over the universe. All thanks goes to DR.Ikhile for the excessive work that he has done for me. Here is his Email solutiontemple27@gmail.com His web site address is http://solutiontemples.com or call his number +27789518085 In any relationship situation you are undergoing through in life, contact DR Ikhile today for speed help and I assure you that as he has done mine for me, he will definitely help you too.thank you Dr Ikhile

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    ReplyDelete
  17. Hello everyone my name is Sophie,i am from Canada I feel very happy to share my great and wonderful testimony with everyone on this platform..: I was married for 4 years to my husband and all of a sudden another woman came into the picture he started hating me and he was abusive and all because i never bear him a child. but i still loved him with all my heart and wanted him at all cost.... He filed for divorce and my whole life was turning apart and i didn't know what to do, he moved out of the house and abandoned me all alone,one day a very close friend of mine told me about trying spiritual means to get my husband back,so i went online to search and i came across so many spell caster who only wasted my time and took a lot of money from me,but i went back to her and told her that spiritual way has only taking my money and not yielding anything, and she  introduced me to a spell caster,drgurulovespelltemple@yahoo.com, so i decided to try it. although i didn't believe in all those things because of what i have gone through lately,i contacted the Doctor and explain all my problems to him and he told me that i shouldn't worry that when he cast the spell on me and my husband that my husband is going to run back to me and that within 3weeks am going to get pregnant,so i did the little he ask me to do and behold it all work out,my husband run back to me and right now we have Twins boy and a girl,so all thanks to Dr Guru you're indeed a great spell caster, in case anyone needs help here is his email address; drgurulovespelltemple@yahoo.com His spells is for a better life OR whatsapp him now +2349023365076

    ReplyDelete

  18. I made a promise to tell my testimony all over the globe once my man come back to me and my husband came just as DR Iwisa told me when he helped me. I made the right choice to have contacted DR Iwisa the great spell caster who is capable of helping you solve your problems. My man left me to suffer and i never believed that he will come back to me again but when i contacted DR Iwisa he assured me that my man will come again. he gave me some list of items to buy but i could not get them in my country and so i sent him the money and he bought the items and prepared the perfect love spell. My husband ran back to me in 3 days time begging for forgiveness THIS IS SO REAL AND GENUINE. I was so surprise that the spell worked just as he told me. This is so amazing and i want you to believe because DR Iwisa is so real and i urge you contact him now on his email so that he can also help you the way he helped me. email is superiorspellhome@gmail.com and you can also contact him with his phone Call & WhatsApp+27730886631

    ReplyDelete
  19. Hello everyone my name is Sophie,i am from Canada I feel very happy to share my great and wonderful testimony with everyone on this platform..: I was married for 4 years to my husband and all of a sudden another woman came into the picture he started hating me and he was abusive and all because i never bear him a child. but i still loved him with all my heart and wanted him at all cost.... He filed for divorce and my whole life was turning apart and i didn't know what to do, he moved out of the house and abandoned me all alone,one day a very close friend of mine told me about trying spiritual means to get my husband back,so i went online to search and i came across so many spell caster who only wasted my time and took a lot of money from me,but i went back to her and told her that spiritual way has only taking my money and not yielding anything, and she  introduced me to a spell caster,drgurulovespelltemple@yahoo.com, so i decided to try it. although i didn't believe in all those things because of what i have gone through lately,i contacted the Doctor and explain all my problems to him and he told me that i shouldn't worry that when he cast the spell on me and my husband that my husband is going to run back to me and that within 3weeks am going to get pregnant,so i did the little he ask me to do and behold it all work out,my husband run back to me and right now we have Twins boy and a girl,so all thanks to Dr Guru you're indeed a great spell caster, in case anyone needs help here is his email address; drgurulovespelltemple@yahoo.com His spells is for a better life OR whatsapp him now +2349023365076

    ReplyDelete
  20. I'm so excited my broken Marriage has been restored my ex husband is back after he left me and our 2kids for another woman. i was so happy to met Dr. OKu how he help many people to bring there Lover back so i contact him to help me too. that was how Dr. Oku help me to bring my husband back.. A big thank to you Dr. Oku because I never thought my ex Husband will be back to me so quickly with your spell. You are the best and world greatest. if you are here and you need your Ex Lover back or your husband moved to another woman, do not cry anymore, contact this powerful spell caster now. Here’s his contact:Email him at: okutemple@gmail.com You can also Call/WhatsApp:+2347053113465

    ReplyDelete
  21. I'm so excited my broken Marriage has been restored my ex husband is back after he left me and our 2kids for another woman. i was so happy to met Dr. OKu how he help many people to bring there Lover back so i contact him to help me too. that was how Dr. Oku help me to bring my husband back.. A big thank to you Dr. Oku because I never thought my ex Husband will be back to me so quickly with your spell. You are the best and world greatest. if you are here and you need your Ex Lover back or your husband moved to another woman, do not cry anymore, contact this powerful spell caster now. Here’s his contact:Email him at: okutemple@gmail.com You can also Call/WhatsApp:+2347053113465

    ReplyDelete
  22. I want to use this great opportunity to thank Dr OSOFO for helping me to get my girlfriend back after 7 months of breakup. My girlfriend breakup with me because he see another boy at his working place and told me he is no longer interested in me and live me in pain and heart break. I seek for help on the internet and i saw so many good talk about this great spell caster Dr OSOFO and I contacted him also and explain my problems to him and he cast a love spell for me which i use to get back my girlfriend within the period of 48 hours and i am so grateful to him for the good work he did for me,that is why i also want to let everyone who is in need of help out there to also seek help from him so he can help.His email;(osofo.48hoursolutioncenter@gmail.com )  or whatsapp: +2349065749952 

    ReplyDelete
  23. I want to thank Dr Emu a very powerful spell caster who help me to bring my husband back to me, few month ago i have a serious problem with my husband, to the extend that he left the house, and he started dating another woman and he stayed with the woman, i tried all i can to bring him back, but all my effort was useless until the day my friend came to my house and i told her every thing that had happened between me and my husband, then she told me of a powerful spell caster who help her when she was in the same problem I then contact Dr Emu and told him every thing and he told me not to worry my self again that my husband will come back to me after he has cast a spell on him, i thought it was a joke, after he had finish casting the spell, he told me that he had just finish casting the spell, to my greatest surprise within 48 hours, my husband really came back begging me to forgive him, if you need his help you can contact him with via email: Emutemple@gmail.com or add him up on his whatsapp +2347012841542 is willing to help any body that need his help.
    Website: http://emutemple.website2.me/

    ReplyDelete
  24. After being in relationship with my wife for years, she broke up with me. I did everything within my reach to bring her back but all was in vain, I wanted her back so badly because of the love I had for her, I begged her with everything, I made promises but she refused. I explained my problem to my friend and he suggested that I should rather contact a spell caster that could help me cast a spell to bring her back , I had no choice than to try it. I messaged the spell caster, and he assured me there was no problem and that everything will be okay before three days. He cast the spell and surprisingly on the second day, my wife called me. I was so surprised, I answered the call and all she said was that she was so sorry for everything that had happened she wanted me to return to her. She also said she loved me so much. I was so happy and went to her that was how we started living together happily again. The spell casters email is :dr.okisinsolutiontemple@gmail.com , or whatsapp/call_ +2348109374702 You can email him if you need his assistance in your relationship or any Other Case.1) Love Spells......2 Divorce Spells.....3 Marriage Spells......4 Binding Spell....5 Breakup Spell......6 Death spell.......7 win a court case spellContact this great man if you are having any problem for a lasting solutionthrough his whatsapp number +2348109374702 

    ReplyDelete
  25. How i was able to have my ex back with me again


    Hello everyone i want to testify of the great and powerful spell caster named Dr IYAYA who brought back my ex who left me and got engaged to another girl,We where happy together when all of a sudden he just change he used to call me every morning and and night before going to bed but all that stopped when i call him he yell at me and told me he didn't want to have anything to do with me anymore i was so sad and confused i didn't know what to do then i went online to search on how to get back my ex then i found an article where someone was talking about how the great and powerful Dr IYAYA helped her and she left his email address i took it and contacted him i told him my problem he only smiled and told me to relax everything will be OK i did everything he asked me to do and he assured me that after 24hrs he will be back,To my greatest surprise the next morning it was my boyfriend he came back knelling and begging for me to accept him back now we are so happy together he can also help you contact him Here: Doctoriyaya@gmail.com you can also reach Dr IYAYA throungh WhatsApp Number: +2347032756397
    If you wish to know more about Dr IYAYA visit he website you may found your solution there www.https://dr-iyaya-herbal-remedy.webnode.com

    ReplyDelete
  26. HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

    This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  his  over_blog http://supernaturalspell1.over-blog.com/

    ReplyDelete
  27. HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

    This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  his  over_blog http://supernaturalspell1.over-blog.com/

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  37. Hello my name is Kallya from USA i want to tell the world about the great and mighty spell caster called Priest Ade my husband was cheating on me and no longer committed to me and our kids when i asked him what the problem was he told me he has fell out of love for me and wanted a divorce i was so heart broken i cried all day and night but he left home i was looking for something online when i saw an article how the great and powerful Priest Ade have helped so many in similar situation like mine he email address was there so i sent him an email telling him about my problem he told me he shall return back to me within 24hrs i did everything he asked me to do the nest day to my greatest surprise my husband came back home and was crying and begging for me to forgive and accept him back he can also help you contact
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